Corporate Strategy
How BIOT sets direction as a Nasdaq-listed holding company: capital strategy, portfolio design, and the decisions behind the group structure.
Articles on this topic
Last updated:
Explainers·
What is BIOT? INSTINCT BIO TECHNICAL COMPANY HOLDINGS INC., explained
BIOT is the Nasdaq ticker symbol of INSTINCT BIO TECHNICAL COMPANY HOLDINGS INC., a holding company incorporated in the Cayman Islands whose ordinary shares began trading on The Nasdaq Stock Market on 24 July 2026. Its operating businesses originate in Japan and span research and development, sourcing, manufacturing, regenerative medicine-related technologies, cosmetics, wellness and consumer brands. It is a separate legal entity from its operating subsidiaries, including INSTINCT BROTHERS.
ReadExplainers·
What does vertical integration mean in biotechnology?
Vertical integration means a single group owns consecutive stages of its value chain rather than buying them from third parties. In biotechnology that typically means research, materials sourcing, manufacturing, brand development and distribution sitting inside one corporate structure. The practical effect is control: one quality standard, traceability from material to finished lot, and faster iteration between research and product. It does not, by itself, make any product more effective, and it does not replace regulatory approval.
ReadCEO Essays·
On My IPO Day, I Ate Dinner at Home as Usual
"How did you celebrate your IPO day?" My honest answer: I didn't. On July 24, 2026, our company began trading on Nasdaq. That evening, I had an ordinary dinner at home.
ReadCEO Essays·
To Bring Joy to Friends — How My Name Became My Life
My parents chose characters that mean "to bring joy to friends." As a boy in Shimonoseki, a port town in western Japan, I simply could not study. Reading without understanding, failing at arithmetic — all I had was sports. When my junior high school had no soccer club, I switched to basketball, practiced relentlessly, and made the prefectural select team.
ReadCEO Essays·
Zero English, and a Plane to Canada 15 Days After Graduation
Fifteen days after graduating from high school, I was on a plane to Canada. I could not speak a single word of English. The trigger was one offhand remark from someone I respected: "Why not go study English abroad?" The moment I heard it, one thought arrived — why not, indeed.
ReadCEO Essays·
I Cried for a Month in Saskatoon — The Uses of Homesickness
My Canadian destination was Saskatoon — freezing winters, only a few dozen Japanese residents in town. An eighteen-year-old who knew only sports, with zero English, I spent my first month homesick and in tears. People only get serious when there is nowhere to run.
ReadCEO Essays·
"Why Not?" — The Single Remark That Changed My Life
Every turning point in my life began with someone else's casual remark. "Why not study English abroad?" sent me to Canada. "There's someone I'd like you to meet" introduced me to my lifelong business partner.
ReadCEO Essays·
No Soccer Team? Then Reach the Top in Basketball
In elementary school I lived for soccer — but my junior high school had no soccer club. A moment where sulking would be understandable. Instead, I started basketball and practiced relentlessly: mornings, evenings, holidays.
ReadCEO Essays·
Why We Won Small Tournaments and Lost the Big Ones
My boyhood soccer team won almost every local tournament — yet at the big tournaments, we always lost. Winning small but losing big: I've carried that frustration for forty years. Small stages can be won on individual talent; big stages are decided by total preparation and team design.
ReadCEO Essays·
From a Perfume-Loving Teenager to a Cosmetics Chairman
I loved perfume as a high schooler — just a simple "like," with no career calculation. Yet when I job-hunted after Canada, I chose a perfume maker from six offers, because I wanted to work near what I loved. The product development I learned there opened the door to a TSE-listed company, then to my own cosmetics business, and now forms the foundation of BIOT.
ReadCEO Essays·
What I Learned at a Tokyo Stock Exchange Company
My product development experience earned me a place at a company listed on the First Section of the Tokyo Stock Exchange. There I saw a world that runs not on individual hustle but on systems — for quality, approval, responsibility. But once I ran my own company, I understood: a company without systems dies when its founder falls.
ReadCEO Essays·
The Day Two Men at Rock Bottom Started with Part-Time Work
When I met our Senior Managing Director, I was in the hardest stretch of my own life — and he was at rock bottom too. Two people at the bottom usually just lick each other's wounds. "Let's climb up together!" — we worked part-time jobs side by side while stacking up challenge after challenge.
ReadCEO Essays·
A Company Is a Work of Art — Why I Build Our Websites Myself
A confession: every website in our group — the holding company's, each subsidiary's, and this very series page — I built with my own hands. "Is that a chairman's job?" I've been asked. My answer is firm: this is precisely the chairman's job.
ReadCEO Essays·
Designing a Company on the Five Elements
Our group is designed on the five elements of Eastern philosophy — wood, fire, water, metal, earth. Wood (INSTINCT BROTHERS) grows products and brands; fire (INSTINCT RAS) ignites talent; water (HIROKI GLOBAL) carries trusted materials from around the world; metal (ARTISANS PRODUCTION) transforms materials into products; and the earth — our holding company — supports them all. Standard org charts describe functions; I wanted to design the company as a living organism, where each element generates the next and the whole circulates.
ReadCEO Essays·
Why Celebrating in Advance Starts the Brain's Engine — The Science of Yoshuku
Let me examine our practice of yoshuku — celebrating in advance — from the brain's side. Honestly: "dream it and it comes true" is not supported by science; research reports that merely fantasizing about achievement can trick the brain into feeling it already has the prize, draining energy for action. Studies suggest those who vividly picture the desired future and squarely face present obstacles — psychologists call it mental contrasting — act the most.
ReadCEO Essays·
Dopamine Fires on Approach, Not Arrival — The True Nature of Excitement
Research on dopamine, the brain chemical deeply tied to drive, reports a crucial property: it works more strongly while approaching an anticipated reward than at the moment of receiving it. The brain burns hottest not when it has obtained, but while it feels itself closing in. This matches my fifty years of experience exactly — the days running toward our listing were hotter than the listing day itself.
ReadCEO Essays·
Smiles Are Contagious — A Leader's Face Is a Corporate Asset
"If I am not smiling, no one around me will smile" — my conviction apparently has scientific backing. Psychology has long studied emotional contagion: people unconsciously mirror the expressions and vocal tones before them, and the mirrored expression moves their own emotions in turn. The facial feedback effect — we don't only smile because we're happy; smiling can nudge happiness — has been studied for decades.
ReadCEO Essays·
Writing Orders the Mind — The Science Behind Management by Essay
When our executives wrote their life essays, one said: "I finally organized what my life has been." That sense of writing-as-organizing has a research pedigree. Psychology has long studied the effects of repeatedly writing about one's own significant experiences; a well-known line of studies reports beneficial changes in people who wrote for some minutes daily across several days. Writing gives swirling events the shape of a story — with a beginning and an end — and a shaped experience leaves the whirlpool of rumination and settles onto a shelf.
ReadCEO Essays·
Motivation Can Be Managed — My Daily Routine at Forty-Five
To close the first half of Season 1.5, let me publish my own daily brain-maintenance routine — nothing special, everything with a reason. Morning: look at the blueprint of the future and confirm today's work is part of it, igniting the approach state. Order tasks by closeness to the blueprint, not by mood.
ReadCEO Essays·
Connection Is Health — The Science of Companions Who Rejoice Together
This half of Season 1.5 closes by grounding our philosophy — "cherish the companions who rejoice together" — in the science of health. A famous research synthesis integrating data on hundreds of thousands of people compared predictors of long-term health and longevity and reported that the richness of social connection was among the strongest, with loneliness argued to rival widely known lifestyle risks. The director of a celebrated decades-long study of adult life concluded that what most determines happiness and health is neither wealth nor fame, but good relationships.
ReadCEO Essays·
The Brain Writes While You Sleep — Sleep and Memory
The next ten essays are original pieces in which I retell what brain science has shown in my own language as a manager and a man. Neuroscience reports that memory is consolidated not at the moment of learning but during sleep: the sleeping brain replays the day, moves what matters onto long-term shelves, and discards the rest. Learning does not end at the desk; it is completed in bed.
ReadCEO Essays·
Ideas Arrive When You Walk — Movement and the Brain
Good ideas do not arrive at the desk; they arrive while walking — and that is not merely a feeling. The effect of exercise on the brain is among the most active research areas of recent years: aerobic activity is reported to enhance factors supporting the growth and survival of neurons, with benefits for memory-related regions, mood stability and concentration, and experiments have reported broader idea generation while walking. Until I left for Canada at eighteen I was nothing but an athlete; I could not study, but I never stopped moving my body — and perhaps those years built the foundation of my brain.
ReadCEO Essays·
One Breath Switches the Body — The Physiology of Tension
Before any big moment I do exactly one thing: exhale slowly and long. Research on the autonomic nervous system shows that inhaling and exhaling shift heart rate and bodily state; a slow, extended exhale is reported to support the calming side of the system. When tension shortens the breath, the body concludes "danger" and thinking narrows; deliberately lengthening the breath sends the opposite signal from body to brain.
ReadCEO Essays·
Why the Brain Says "Tomorrow" — The Anatomy of Procrastination
Procrastination is not weak will; it is the natural consequence of how the brain values time. Behavioral economics repeatedly confirms that people steeply discount the future: the same reward feels smaller when distant, while a small pleasure at hand looms large. "Success in three years" loses to "one more drink tonight." The human brain comes fitted with a lens that shrinks whatever is far away.
ReadCEO Essays·
We Grow Strong Because We Laugh — Laughter and Stress
When I say we exist to increase the world's total volume of smiles, it is not a sentimental slogan; laughter does measurable work in the body. Studies report lower indicators of stress-related hormones in states of laughter and positive emotion, along with changes in pain perception and immune markers. The magnitude and conditions remain carefully debated, but the direction — that laughter moves bodily state — is widely supported.
ReadCEO Essays·
Name the Fear and It Shrinks — On the Amygdala
Becoming the chairman of a listed company does not remove anxiety. Because it does not, I learned how to handle it. Neuroscience reports that attaching verbal labels to emotion is accompanied by reduced activity in the amygdala, the region tied to fear and anxiety — a phenomenon called affect labeling.
ReadCEO Essays·
Meaning Over Reward — The Research on Intrinsic Motivation
My answer: raise it, yes — but pay alone is not enough. Psychology has reported that adding external rewards to behavior people already enjoy can reduce the motivation welling up from within, and a widely known framework holds that sustained effort requires a sense of deciding for oneself (autonomy), of getting better (mastery), and of doing something that matters (purpose). I have watched this on the floor for decades: at the same salary, the person who is trusted with a decision grows; at the same task, the person who knows whom it is for endures.
ReadCEO Essays·
The Brain Can Change at Any Age — Plasticity as Hope
Season 1.5 closes with the one line I most want to leave: the brain can change at any age. It was once believed that adult brains were fixed. Neuroscience has repeatedly shown otherwise — neuroplasticity, the continual remaking of neural connections through experience and learning.
Read